Diplomacy Zine -- EP #173 Chapter Five From: Eric_S_Klien@cup.portal.com Date: Tue, 05 Jun 1990 04:49:42 +0000 Issue #173 of ELECTRONIC PROTOCOL: ******************************************************************** Contrary to what he had been led to expect by watching hundreds of TV police shows, the precinct station house was drowsily quiet this Saturday morning. A few uniformed officers were standing off in the far corner of the room he entered, quietly talking together. Along the side wall stood four squat blue robots, silent and inert. The Writer paid careful attention the the equipment on the human police officers: pistols, stun wands, gas and concussion grenades, bulletproof vests, protective helmets with built-in radios and shatterproof sliding visors. Yes, he was in New York, all right. ******************************************************************** Chapter One contains: BLITZKRIEG, GETTYSBURG, RED STORM RISING, and COMRADES IN ARMS And is published by daybell@aludra.usc.edu/Donald Daybell Chapter Two contains: DRAGONSLAYER, BISMARK, COLD WAR, JACAL, MANHATTAN, VERSAILLES, and DRESDEN And is published by tedward@cs.cornell.edu/Ted Fischer Chapter Three contains: MULHOUSE, DAWN PATROL, SNIKKEL-2, BERLIN, SNIKKEL-1, EL ALAMEIN, SQUALANE, UNGAWE, CAPTAIN CAVEMAN And is published by cwekx@htikub5.bitnet/Constantijn Wekx Chapter Four contains: FIRE WHEN READY, DREADNOUGHT, JUGGERNAUGHT, BIG WILLIE, NICKEL, and OZARK And is published by lord_zar@ucrmath.ucr.edu/Wayne Wallace ------------- Chapter Five ------------- No game reports in this issue. Publisher comments: Quote from p. 89 of Cyberbooks by Ben Bova. From The Boston Globe Monday, May 21, 1990: CREATING LIFE - FROM SCRATCH Mimicking nature, chemist concocts molecule that reproduces! By David L. Chandler In an ordinary chemical laboratory in Cambridge, a chemist has taken the first small step - small, but dramatic, toward the creation of synthetic life. With a single experiment that a rival scientist says may merit a Nobel prize, MIT's Julius Rebek has created a molecule that does something that only living organisms have been known to do: It reproduces itself. It is an achievement that may shed some light on how all life began, and that may even lead someday to the creation of real, living organisms from scratch. In the meantime, it may also produce a host of useful applications in everything from medicine to chemical manufacturing. Rebek's simple, two-part molecule is capable of attracting copies of its two constituent molecules and holding them together long enough for them to join, forming an identical copy of the "parent" molecule. The original molecule and the copy then split apart, and each can create another copy. Once started, this reproduction takes place a billion times a second. This accomplishment, Rebek wrote tn a scientific paper describing the research, can be considered "a primitive sign of life." It is the first time any scientist has achieved this kind of mimicking of one of the key, distinguishing characteristics of living creatures. The work is "a very interesting and significant development," said Cyril Ponnamperuma, director of the laboratory of chemical evolution at the University of Maryland and one of the leading researchers on the origins of life. The molecule Rebek created is different from the natural molecules of life, and that adds to its importance, said Ponnamperuma. It means that "we need not narrow down the concept of life just to amino acids and nucleic acids. So life is probably very much broader." The work suggests that life on other worlds, with possibly a variety of different chemical bases, could be "much more universal than we think." The self-replication of molecules that forms the basis on all known life is a vastly more complicated process, of course, but it has important similarities to Rebek's experiments. Every living thing contains a molecule of DNA inside every one of its cells. This molecule, whose corkscrew or "double helix" shape has become familiar to all students of biology, contains all of the information that provides a blueprint for the development and functioning of the whole organism. To reproduce, the two-part DNA molecule "unzips," or splits lengthwise into two halves. Each half becomes a template to which the constituent molecules of DNA, called bases, attach themselves. The result is two identical copies of the original double helix. But DNA needs a lot of help to reproduce. A variety of enzymes, small chemical bundles that promote specific chemical reactions, are needed to help the molecule unzip, and to get the bases to line up and attach themselves to each half to make the copy molecules. NO HELP NEEDED One of the remarkable features of Rebek's molecule is that it needs no such help. As long as it is immersed in a "soup" containing the right constituent molecules, it will keep reproducing itself. The molecule mimics the self-replication that is characteristic of life, and although it is related it is chemically different from the molecules that are the basis of life. Rebek's creation is called amino adenosine triacid ester, or AATE, and was designed using a kind of atom-by-atom architecture at the molecular level. Rebek says his molecule was "engineered". He knew what he wanted to accomplish, and figured out the shapes and chemical "stickiness" the molecule would have to have. Over a period of months, working with graduate student Tjama Tjivikua of Namibia and visting student Pablo Ballester from Spain, he synthesized the molecule and, after a few false starts, got it to work as expected. They described the accomplishment in a paper in the Journal of the American Chemical Society. The molecule is made up of two component molecules - an ester and an amino acid - stuck together so it "opens up like a jacknife", Rebek explained. In this shape, the molecule has "sticky" surfaces - which have a propensity to bind chemically with other molecules - at each end. When the molecule is in a solution containing more of its constituents, each sticky surface binds with another ester or amino acid. When the two new molecules have attached to the original "template" molecule in its open-jacknife position, they quickly fuse together in the middle, where each has another sticky surface. And a new, duplicate molecule has been born, attached to the first. The two then split apart because of the natural thermal jostling that takes place between molecules in the test tube, and each can go on to start the process again. THE DRIVING FORCE Many other scientists have attempted to create such a chemical process but none has succeeded. "He beat us fair and square", said chemist Jonathan Sessler of the University of Texas, who has spent years trying to produce a self- replicating molecule. "It's a great coup that he's achieved this. Making the first self-replicating system is a Nobel prize-level accomplishment." The driving force for such research, Sessler explained in an interview last week, is to try to understand better how life came into being. "We look at nature and we see some very complicated processes that almost seem magical." The natural processes are still "one step beyond what we as human beings can do at the moment", and producing a chemical system capable of transmitting genetic information from one generation to the next - Rebek's achievement was the first step - represents "an intellectual challenge of the first order." Rebek hopes his work may someday help scientists understand the basic "code" of life. DNA's blueprints are written in a seemingly arbitrary code in which each sequence of three "letters" - one of four different chemical bases - stands for a specific protein. But there is no apparent connection between the code letters and the structure of the various proteins they relate to. "Thirty years of intensive research has failed to turn up some plausible relationship", Rebek said in an interview in his office at the Massachusetts Institute of Technology. "But you can't help but think that there had to be one." A SEARCH FOR LOGIC He thinks that there may be some underlying connection, and he hopes that work on hybrid molecules such as AATE may help to reveal an underlying logic that can be described in a simple rule that first- year chemistry students will someday be taught; they would be able to glance at a three-letter code and know immediately what protein it represents. That doesn't mean anyone will be able to reconstruct the exact molecules that may have existed 4 billion years ago when life on Earth began. "Some people think the road's washed out" and that it will be impossible to go back and tell exactly how life evolved, Rebek said. "It's pretty hopeless to try to find the original" molecules of life. But Rebek hopes to build much more complicated self-replicating molecules that will help to illustrate how life might have gotten started. He hopes to produce longer chain-like molecules that could carry information, a coded sequence of constituent parts, in a simplified version of the information-carrying ability of DNA. What he has already accomplished could have a variety of practical applications as well. "When an expertise is developed that allows you to design and build molecules that will do what you want", said chemist T. Ross Kelly of Boston College, "that has all sorts of applications." It might lead, he said, to the creation of artifical enzymes that could have important medical applications, perhaps curing conditions that involve an excess or deficiency of specific hormones or other compounds in the body. "The kind of work Rebek and other people are doing is leading to the ability to design enzymes", Kelly said. The same kind of technology could have industrial applications as well, through the creation of enzymes that would foster the production of certain chemicals. Rebek shrugs off such practical possibilities. "That's certainly not my motiviation", he said. "These are academic questions; we're not focused on getting better delivery of a drug or a higher octane fuel." THE ULTIMATE ACHIEVEMENT But the academic research could lead in the direction of what may be one of the most dramatic ultimate achievements imaginable, and perhaps the ultimate expression of scientific hubris; the creation of life itself. Is that possible? "No question about it", says Ponnamperuma, whose own work has concentrated on creating the basic chemical constituents of life, the basic chemical building blocks, under laboratory conditions that mimic the early Earth. "I have no doubt at all", he said, that someday life will be created from scratch in the lab. "Nature took billions of years", he said, "but the mind of man might be able to concentrate that into a short time. How soon, I don't know." From the July 1990 issue of Reason: CANCELING THE POSTAL MONOPOLY By Rick Henderson By simultaneously proposing a 19 percent postage increase and a series of service cutbacks, the U.S. Postal Service has inadvertently fueled the fires for postal privatization. Supporters of deregulation are looking closely at New Zealand's competitive postal service; privatization critics would rather ignore it. New Zealand "corporatized" and deregulated its postal service in 1987. The government maintained ownership of the corporation but ceased subsidies and ended its monopoly on letter delivery. This forced the postal service to operate profitably while facing competitors. The law requires the postal service to continue serving every address in the nation. To restucture its postal service, the government closed more than two-thirds of its post offices and allowed private retailers to set up contract stations. Since decontrol, the net number of post offices has increased by 17 percent. On-time delivery of first-class letters has increased from 84 percent to 99 percent, while automation and contracting out opperations have reduced the postal workforce by one-fifth. Postage rates went up by 40 percent in the two years prior to decontrol; they have been stable since. Yet the postal service has gone from annual losses of $37 million to yearly profits of $76 million. Will studying New Zealand's experience provide lessons for the United States? In the Wall Street Journal, Postal Rate Commissioner John Crutcher said: "U.S. Postal Service officials who go to New Zealand return chastened and silent. The U.S. post office is not the cheapest or the most efficient in the world; it's only the biggest." The following was scribed by loeb@geocub.greco-prog.fr/Daniel Loeb: From Rats #6: Taking the Lepanto's Logical Conclusion by Pete Swanson If you don't know what the Lepanto is, you haven't lived! but for those embryonic readers/players among you, it is basically this: a suggestion from Edi Birsan that Italy can make a suprise direct attack on Turkey by the following moves: Spring 1901: A(Rome)-Apu, F(Nap)-Ion, A(Ven)h Autumn 1901: F(Ion)CA(Apu)-Tun, A(Ven)h. Builds F(Nap) Spring 1902: F(Ion)-EMS, F(Nap)-Ion, A(Tun)&(Ven)h Autumn 1902: F(Ion)&F(EMS)CA(Tun)-Syr, A(Ven)h Turkey is now up the creek without a paddle, provided a) he doesn't move F(Con)-Ank in Spring 1901, and b) Austria attacks Aegean from Greece in Spring 1902. The Lepanto Opening virtually metamorphosed Italy from being a boring, predictable country, to an exciting, unpredictable one. Now, instead of walking virtually suicidally into Trieste or just hanging around for a few years, watching the other countries have all the fun, bouncing your armies in Piedmont and Venice around for kicks, and jumping in on the side of the player with the most units in 1904 or thereabouts, you can play an active part straight from Spring 1901. "Avanti, Luigi--let's swim to Turkey!" and pretty soon, most Italian players were! Lepantos cropped up like dandelions; this became pretty boring, since any Turk who had seen the Lepanto before was going to make fairly good efforts at stopping the initial convoy to (Syr) or (Smy) and then neither Italy or Turkey gets anywhere. Well, it wasn't long before some ex-Turk player invented a stab-Austria variant. Simply fake a Lepanto in Spring 1901, then Turkey tries for Greece, and the Italian convoys to Albania and attempts to slip in the back door into Trieste. With a Russian army floating in/around Galicia, the only real fighting is between Italy, Russia and Turkey over who gets Serbia, the last Austrian haven in Spring 1903. The Austrians are sometimes a shrewd people. Stung by the change of direction, they soon were showing the Italians how to switch the switch. "Hey Luigi, you know you probably won't get a build if you stab me from the Lepanto--I'm just going to be A(Tri)-Alb, keeping you out of both." "Oh..." "Why don't WE get Turkey?" "But me 'an da Sultan, we got dis plan..." "I know all that," interupted the Austrian, "but you want a build don't you?" "Uh, yep." "So I have a better plan in which you're bound to get a build." "Yeah?" "Sure, you move A(Ven)-Tri, A(Rom)-Apu, F(Nap)-Ion and I'll move F(Tri)-Alb, A(Bud)-Ser, A(Vie)-Bud." "Ok, then what?" "Well then, you move A(Tri)-Ser, and convoy A(Apu)-Tun, and I get Greece. You can build your second fleet and move to EMS & ION in Spring 1902, and we'll have Bulgaria beseiged and Turkey scared face-less." "Oh, yeah!" This was the Key Variant, invented by Jeff Key. Basically, Austria and Itlay bluff everyone else on the board into believing that they are at loggerheads, and then suddenly, like magic, they are at Turkey's doorstep. I have recently completed a game where we put together an excellant example of a deviant of the Key variant. This was 1974BZ, started in DER KRIEG in June 1974. I just so happened that Italy (Pete Cousins) and Austria (me) were at a small game con when the gamestart was announced, and of course we got to talking, planning, scheming, plotting, etc---the normal things two dippy freaks do when they get together. After having agreed that we were the two secret masters of British diplomacy, we also agreed that we should try a new, fun, but devastating Austro-Italian opening; this is what we came up with. The initial aims of Diplomacy were clear--we had to get Turkey and Russia at each other's throats. I made strong "alliances" with each of them against the other, claiming a non-aggression pact with Italy. We also cultivated something healthy up north in the other corner of the board--like England stabbing France stabbing Germany stabbing England. Since this Russo-Turkish conflict was essential to the plan, as it is in any Lepanto, the wait for the first season's results was nail-biting. The Spring 1901 moves were: A: A(Vie)-Gal, A(Bud)-Ser, A(Tri)-Adr! I: A(Ven)-Tri!, A(Rom)-Ven, F(Nap)-Ion R: F(Stp)-GOB, F(Sev)-Bla(BOUNCED), A(Mos)-Sev(BOUNCED), A(War)-Ukr T: A(Con)-Bul, F(Ank)-Bla(BOUNCED), A(Smy)-Arm E,F,G: Amusing themselves and leaving us alone. Which moved the GM to comment: "Pet Balloon Burst!" (Pet Balloon was an unearned nickname I had acquired from John Piggott.) I use Lakofkaesque notation in the moves. ! means a move of either certain crassness or sheer brilliance. God knows what Greg Hawes (R) and Mick Bullock (T) thought--hopefully they believed I had stabbed Russia and Italy simultaneously, and VERY badly, and that Italy had stabbed me, and Russia and Turkey had stabbed each other. At least, that's what I told them had happened! The diploming became furious now. I managed to throw myself at the mercy of Greg Hawes. "We're in the same boat now, mate. We both have stabbed and have got stabbed (by the way, heh, sorry about that, ahem). Let's get it together against Italy and Turkey, ok?" Needless to say, I said roughly the same thing to Mick Bullock, but with greater credulity, it seems, especially since he was the one I had NOT plunged by dagger into--"I can hold off Italy while we take care of Russia, but I need another center--how about supporting me into Rumania?" Now came the crunch. Autumn 1901: A: A(Ser)SA(Gal)-Rum, F(Adr)CA(Tri)-Gre!, Builds A(Vie),A(Bud) I: F(Ion)CA(Tri)-Gre!, A(Ven)-Apu, Builds F(Nap) R: A(Ukr)SF(Sev)-Rum(FAILS), F(GOB)-Swe, A(Mos)-Sev(BOUNCE), builds F(StPnc) T: A(Bul)SA(Gal)-Rum, F(Ank)-Bla, A(Arm)-Sev(BOUNCE), builds F(Con) Suddenly, out of the mess that was Austria, arises Phoenix-like from the ashes, a less-mess. However, Turkey looks decidedly more pale than anyone else, since Italy carries out the usual Lepanto convoy moves, but this time Bulgaria get immediate bad flak, and Russia shouldn't like what's going on either. Of course, it helps if you can still keep Russia and Turkey on unfriendly terms, though if they're smart, they'll kiss and make up pretty quick. These moves also show the usefulness of stabbing in the Autumn season of a two-season game [with English rules]. Greg build F(StPnc), which in this case was the most useless unit he could possibly want--however, assuming his plans had gone as expected, he probably would have been able to start an anti-English campaign whilst beating up Turkey with Austria and Italy. As it was, Greg carried on with his somewhat tenuous Austrian agreement (I suppose as an alternative to a non-existant Turkish one) and Mick tried very hard to pull over Greg to his side. But to no avail. Spring 1902 A: A(Vie)-Gal, F(Adr)-Ion, A(Rum)SA(Ser)-Bul, A(Bud)SA(Rum) I: A(Gre)SA(Ser)-Bul, F(Ion)-EMS, A(Apu)-Rom, F(Nap)-TyS R: F(Sev)-Bla(BOUNCE), A(Ukr)SA(Mos)-Sev(BOUNCE), ... T: F(Bla)&A(Bul)SA(Ukr)-Rum(NO SUCH ORDER), A(Arm)-Smy, F(Con)-Aeg By Autumn 1905, Turkey was out, and Russia was left with two supply centers, Liverpool and Edinburgh! (An interesting point: Russia kept these two centers for the rest of the game, and kept F(Bla) supplied from England until Autumn 1911 when the game ended. Until then, I needed four units to keep in penned up and out of my supply centers! Some more funny things about this game: Pete Birks dropped out (not his fault) as England, and then GMed the game from one gameyear later. Austria eventually won; however, I was held to a 16-unit stalemate line for a while, and voted "yes" to a four-way draw with Germany, France, and Russia. But Germany voted "no" hoping to break me down with French help. He then changed his plan, decided he would like a two-way draw with me, suddenly switched direction just as I was having what I thought was a last-ditch effort to sneak in the other two centers I needed!) Now, I'm certainly not recommending that you all go out and try exactly this opening in your next game. Firstly, anyone who has read this article [or the gamer's guide] will know what's going on. Secondly, I'm not certain that the opening is tactically ideal. (Why not just convoy, A(Apu)-Gre from the standard Lepanto for example?) However, I hope this opening will show a different attitude to the game than most people subscribe to, ie: the standard opening CAN get just a teensy-bit tedious, and make the game stereotyped. A far out play like this can give more fun and interest, and above, can work! ((The opening has been correctly summarized as generally being a load of rubbish BUT it equally shows that given the right situation anything can work, and work well. I don't imagine that you'd be so fortunate as to find such a pair of players playing R&T as occured in this game. Although to be fair it was Russia who misplayed.)) ((A good diplomay player is a player who is willing to change any ideas he has at the start of the game due to who the other players are and what they say. Nothing is sacred, but some openings are tactically sounder than others.)) ((The main problem facing Austro-Italian alliances is the Russo-Turkish alliance, it slows down the advance to what may be a mere trickle or even complete stalemate. Still, this is much better than the alternative which is a three-way attack on Austria. I have no stats, but it would be interesting to learn how these three-way alliances split up in latter years. Are there more Russo-Turkish alliances or Italian-Russian alliances? As I was saying Lepanto openings at least enable A/I to mobilize their forces as quickly as possible against a R/T alliance.)) I am enjoying publishing this zine. Keep that mail coming! Eric Klien Up